No doubt one pocket will improve your overall game, as mentioned primarily in the areas of safety play, cueball control, pattern play and banking. You also train your eye to recognize all those two-way shots that will come up, albeit less often, in rotation games.
In safety play, you learn to really snuggle the ball into tight spots. I'm talking about frozen ball marriages. With the advent of the jump cue and superb kicking of some opponents, this may be a game changer in rotation, as evidenced in the recent Mosconi Cup. One hole will also teach you patience and the calculation of risk vs. reward odds.
If feasible, when switching to rotation, I always run through a few racks on the practice table with some stroke shots included. Hit everything crisp and firm. This gets the "bunt" mentality out of your mind, and if you've played plenty of rotation in your life, it doesn't take long for the brain to automatically re-adjust to the stroke dynamics required for rotation based on my experiences.
Good luck and best wishes.
~Razor