I love this question! Makes everyone think, a little!
A lot depends on how tightly the balls are racked, where they're placed and the angle of the rack (some people don't see very straight and the rack gets sorta cockeyed), from where you hit the cue ball, how hard you hit the cue ball, where the cue ball first makes contact... There are a LOT of variables on this one!
I would suggest that if you are wanting to do something in particular, pay close attention to what you do on every break. Write down all the variables and the results. When you find the break you want, work on repeating it. Most of us have a break that is common to us. If we want to change what results are normal for us, we have to change the approach.
Some folks set up the balls according to their break... Stripes here, solids there... Then, they break and run out on you, because all their balls are in the perfect locations for easy shots. (I'm assuming this might be what you're wanting to do?) If you watch them closely, you'll learn how NOT to rack the balls for them, if you ever get the chance to rack the balls.
Good luck finding the break you are looking for!