I used to make cocobola cues all the time and never was effected until I made about 6 cues at one time and it ate me up. I quit maked for several years and then one day someone ordered one and I had to make it, no problem.
As long as I only make one every so often and wash real good after I do then I do not have any problems. I do leave the room while the CNC does the cutting and have a filter system that takes the dust out of the air.