Handicapping straight pool is very difficult. It is easier at the beginner through intermediate levels, because the "outlier" runs won't usually decide a game. If two beginners (though not exactly equal in speed) play a race to 100, someone might run 16 - but not 60. Therefore, a small handicap between them might work very well.
Once you get to the higher levels, where the outlier runs might be, say, runs of 100 or more, handicapping becomes very difficult. They might work over the long run, but in any given game they can simply appear silly. The lower-ranked player might have a huge run and win the game by a tremendously lopsided score.
Of course, it is the uniqueness of 14.1 that causes this - the ability to hold the table for long periods of time without letting your opponent get a chance. This is much more rare in rotation games, because the higher-skilled player will get more chances at the table to outplay the opponent.
- Steve