I don't hit people up but I'll give you my opinion.
The following is a complex thought process, but this is pretty much the logic of making a decision:
1.)If you are faced with a hard shot and a hard safety, first try to determine if making the shot will benefit you. If it doesn't help you get closer to winning the game, then consider not taking it.
2.) If you feel that making the shot would benefit you, then try to determine what the result might be if you attempt the shot and miss. You may be able to manipulate the speed to turn it into a two-way situation where if you miss, you don't leave your opponent a shot.
2.)If you don't see it as a two-way situation, or can't figure it out, then look for a safety. As you know, the object of a safety shot is to prevent your opponent from pocketing a ball. If you feel that the safety is a low percentage shot as well, then try to figure out what you might possibly leave your opponent if you miss the safety.
3.) Now evaluate both situations. If both are equally as hard to accomplish but one will will possibly leave your opponent tougher if you miss or fail, pick that one.
4.) If you can't figure out what might happen if you miss the shot or the safety, then you are going to be hoping for luck. The better skilled you are, the less you will be relying on luck. At some point, all players of all skills will face a situation where they will have to hope for some luck.
5.) Once you decide that you will have to hope for some luck, then you should probably just go ahead and take the shot. By taking the shot, you will have 2 opportunities for good luck. One is that you will make the shot and stay at the table. The second is that you will miss the shot but leave your opponent tough.
If you decide on trying the difficult safety, you only have one opportunity for good luck, which is that you will leave your opponent tough. But you will be leaving the table.
Regarding this decision process: It doesn't matter what your skill level is. The process is basically the same and you will make your decisions based on your level of skill.