EDIT: Except, apparently the BCAPL rules (thanks, Buddy Eick). The WPA World Standardized Rules don't say the same thing. Here's what I found there:
"1.6 Standard Call Shot
In games in which the shooter is required to call shots, the intended ball and pocket must be indicated for each shot if they are not obvious. Details of the shot, such as cushions struck or other balls contacted or pocketed are irrelevant. Only one ball may be called on each shot. For a called shot to count, the referee must be satisfied that the intended shot was made, so if there is any chance of confusion, e.g. with bank, combination and similar shots, the shooter should indicate the ball and pocket. If the referee or opponent is unsure of the shot to be played, he may ask for a call. In call shot games, the shooter may choose to call ?safety? instead of a ball and pocket, and then play passes to the opponent at the end of the shot. Whether balls are being spotted after safeties depends on the rules of the particular game."
This might suggest you can't do both in the same shot, but it isn't definitively clear like the BCAPL rules.
I haven't seen anything in the VNEA rules quoted here so far that clearly prohibits calling a ball and a safety together. Without a clear rule or regulation (like the BCAPL rule) I think it could logically be determined either way by a referee.