Sure. Regional level and national tournaments. That's not what the OP is talking about. We're discussing the best way to run a weekly room tournament.Been too many non handicapped tourneys that were full.
Using the FargoRate handicapping charts, you can pick the advantage you want the better player to have, like 0-10% or 10-20%. I think most players will be OK with the stronger player having a 15% advantage -- that still gives them a reasonable chance to win.
Handicaps for weekly pool tournaments are discussed in this video: