I think we all gamble to a degree, most of us pay an entry into a pool tournament to try to multiply our stake, its dressed up but its still gambling. Many on here like a flutter in the casinos too, and of course buying a house is the biggest gamble in most peoples lives.
It's ironic that many people have lost their house (my father included once!) through gambling yet buying a house is often the biggest gamble of most peoples lives. Interest rates can go up making the payments unpayable as happened in the UK not all that long ago, it happened in Thailand even more recently, or even worse the market could collapse leaving you owing a debt much greater than the value of the home. Putting your money in a bank is a gamble, buying stocks certainly is.
There's no bigger stake than your life, getting into your car or flying in current times could result in the ultimate loss!
Excessive gambling, like eating, drinking, etc certainly isnt good for you! But there's no reason why gambling in moderation should be any more risky than playing the lottery, or dream tax as it should be called.