This is a very awkward scenario but I do like this shot best. My concern is that there is a chance of leaving a return safety that will leave me worse off than I am now.
After this safety, your opponent is going to try and play a one rail kick at the 9ball hoping to leave the cueball in the lower left corner area. If the 2ball is now easier to pocket in the side, he's going to have to get a little more aggressive.
Trying to run out from here is challenging but worthy of consideration. You absolutely have to make sure you get a shot on that 4ball (preferrably straight). That's possible but the safety is definitely easier. The only problem with the safety is, it really doesn't guarantee victory though you do force your opponent to come up with a good shot.
The kick-safe on a barbox is a great idea. A lot of big table players forget how easy kick-safes can be on a barbox. Based on the layout of this diagram, I'm not very fond of the kick-safe because the 2/4 seem to block a portion of the appropriate path. Even for a barbox, this shot is also a bit difficult to judge. I think it shows excellent imagination to consider the kick but not great judgement to shoot it. TX Poolnut's safety is just far more predictable and just as effective.