I don't see how. Player's responsibility after their shot is to activate their opponent's clock by clicking the button on their side. Someone's time is ALWAYS running. Set the per-player time to account for racking and cleaning the ball a few times, and you know EXACTLY the longest time a match can run. If Corey Deuel wants to ask for the CB to be cleaned 10x during the match, he is perfectly welcome to, as that runs down his clock while he is not shooting.
See my other post right above. If the opponent forgets to hit their clock and it continues to run, this leads to time crunch late in the match for that player. Sounds like it could be an absolute game changer for streamed/televised matches. What pool needs is faster matches, less safety play, and more pressure. A chess clock would solve all these issues. Don't put the remaining time directly in a player's view while they are playing, but hook it up to the stream/television feed, so commentators can play up the time angle. I see absolutely no downsides.
Little kids manage this in chess tournaments without an issue, so pool players might have a shot.