Hi Cameron,
Firstly I think it is constructive to have debaters playing the role of devil's advocate. It tends towards more penetrating insights to provide evidence for arguments. Ii do this myself from time to time but haven't had the good sense to offer my opinions as devil's advocacy
Now to the point!
I believe non-OB-focus on delivery is not only possible, but potentially advantageous. But it won't be for the weekend hack, or even the mid-level pro. It will be something that can only be performed at elite levels of play by someone with a deep understanding of all alignment and compensation factors.
The main reason more do not attempt it, is they are not aware of the importance of bridge point positioning, nor of the various effects of spin, speed, bridge length, sweep and CB to OB distance. If they knew how to pre-calculate for all these things, they could pre-align and simply shoot at the CB. Then look up to observe their handiwork
But of course that is a trek away, so no one here is likely to make the step successfully with a few sessions of practice. They need a much firmer base of knowledge to bridge that gap, from the world of Intuitive Adjustments to a world of Systematic Prediction.
The Calculator